J Korean Ophthalmol Soc.  2004 Mar;45(3):413-418.

The Effect of Intravitreal Triamcinolone Acetonide on Cystoid Macular Edema

• Lee J
• Lee JH

Abstract

PURPOSE
To investigate the use of intravitreal injection of triamcinolone acetonide for the treatment of cystoid macular edema (CME) of various causes. METHODS: Thirty one patients with CME were participated in this study. Six patients were with diabetic retinopathy, seven were with branch retinal vein occlusion, six were with central retinal vein occlusion, seven were with uveitis, and five were with tractional membrane. At first and third month after injection of triamcinolone acetate (4 mg/0.1cc), best corrected visual acuity and thickness of macula by OCT-3000 (Zeiss) were measured. The results were analyzed by paired t-test (SAS 8.0 version). RESULTS: Average best corrected visual acuity was 0.17 0.08, and average macular thickness was 524 +/- 122 micrometer before injection. At first month after injection, the results were 0.33 +/- 0.12 and 309 +/- 150 micrometer. At third month after injection, the results were 0.38 +/- 0.15 and 304 +/- 156 micrometer. Eventhough transient increase of intraocular pressure happened in one eye, there were no complications affecting visual acuity. Injection of triamcinolone acetonide was effective especially in the patients with branch retinal vein occlusion and uveitis. CONCLUSIONS: Intravitreal injection of triamcinolone acetonide for the treatment of CME of various causes showed improvement of visual acuity and anatomic recovery. Study with longer observation and more participants may be necessary for further evaluation.

Keyword

Cystoid macular edema; Intravitreal injection; Triamcinolone acetonide

MeSH Terms

Diabetic Retinopathy
Humans
Intraocular Pressure
Intravitreal Injections
Macular Edema*
Membranes
Retinal Vein
Retinal Vein Occlusion
Traction
Triamcinolone Acetonide*
Triamcinolone*
Uveitis
Visual Acuity
Triamcinolone
Triamcinolone Acetonide