J Korean Ophthalmol Soc.  1999 Jan;40(1):176-181.

Clinical Aspects of Infectious Endogenous Endophthalmitis

Affiliations
  • 1University of Ulsan, Asan Medical Center.
  • 2Capital Army Hospital.

Abstract

Infectious endogenous endophthalmitis is a relatively rare, but seriously devasting disease. To evaluate clinical aspects of this disease, we performed a retreospective study on 7 eyes of 7 patients who had been treated with this diagnosis from July 1994 to January 1998 at Asan Medical Center. The preceding systemic diseases consisted of liver abscess, non-small cell lung cancer, spontaneous bacterial peritonitis, acute cholangitis, cystitis, systemic candidiasis. Microorganisms were recovered in blood culture in 4 of them(3 Klebsiella pneumoniae and one Candida albicans). One among these patients also revealed culture positive for Klebsiella pneumoniae in the vitreous as well as in his blood. All patients received intravitreal vancomycin and amikacin injection following vitreous and aqueous tapping. Four patients underwent pars plana vitrectomy as the second procedure and 2 of them expired. At the final follow up, retina remained attached succesjully in six of 7 eyes, yet the visual outcome was so poor that only two recovered over 5/200 or better. Infectious endogenous endophthalmitis has guarded prognosis since causative microorganisms are often extremely virulent, detection of this disease is likely to be delayed and appropriate management can not be started immediately. High index of suspicion for the diagnosis and the intensive treatment are strongly suggested to achieve the best result.

Keyword

Infectious endogenous endophthalmitis; Intravitreal antibiotics injection

MeSH Terms

Amikacin
Candida
Candidiasis
Carcinoma, Non-Small-Cell Lung
Cholangitis
Chungcheongnam-do
Cystitis
Diagnosis
Endophthalmitis*
Follow-Up Studies
Humans
Klebsiella pneumoniae
Liver Abscess
Peritonitis
Prognosis
Retina
Vancomycin
Vitrectomy
Amikacin
Vancomycin
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