J Korean Ophthalmol Soc.  1998 Jan;39(1):216-220.

A Case of Stevens-Johnson Syndrome after Acetazolamide Use

• Lee JH
• Lee SJ
• Kim YH

Abstract

Erythema multiforme is an episodic, self-limited, mucocutaneous, inflammatory disorder and the disease manifests as severe form is called Stevens-Johnson syndrome. It is most commonly precipitated by herpes simplex infection or drugs and the pathogenesis of the mucocutaneous lesion is thought to be related to immune complexes, cell-mediated immunity, or both. We experienced a case of Stevens-Johnson syndrome in 23-year-old female who had systemic bullous kin lesion and diffue mucopurulent conjunctivitis after use of oral acetazolamide for control of steroid-induced increased intraocular pressure after excimer laser photorefractive keratectomy, which has not been reported in Korea. So, we report this case with a review of the literature.

Keyword

Acetazolamide; Excimer laser photorefractive keratectomy; Stevens-Johnson syndrome

MeSH Terms

Acetazolamide*
Antigen-Antibody Complex
Conjunctivitis, Bacterial
Erythema Multiforme
Female
Herpes Simplex
Humans
Immunity, Cellular
Intraocular Pressure
Korea
Lasers, Excimer
Photorefractive Keratectomy
Stevens-Johnson Syndrome*
Young Adult
Acetazolamide
Antigen-Antibody Complex