Clinical Studies on Purpura in Children

Han, Change Soo; Park, Seong Won; Kang, Yong Seob; Lee, Cheol Ho; Kim, Youn Ki

Abstract

This is a clinical study on 72 cases of purpura hospitalized at Han Il Hospital during the period from Jan., 1970 to Dec, 1979. The authors obtained the following results : 1) Allergic purpura (25 cases, 34.7%) was the most common disease, followed by I.T.P. (20 cases, 27.8%), Ieukemia (10 cases, 13.9%), meningoccemia (7 cases, 9.7%), and aplastic anemia (5 cases, 6.9%) in order of frequency. 2) The most prevalent age group was 6 to 9 one (45 cases), and sex ratio of male to female revealed 1.67 : 1(45:27). 3) The main clinical features in thrombocytopenic purpura were anemia abdominal pain fever and epistaxis ; while those in non-thrombocytopenic purpura were abdominal pain fever melena hematuria and headache. 4) The hemoglobin level was below 7 gm.% in leukemia and aplastic anemia, but normal or slightly decreased in allergic purpura and idiopathic thrombocytopenic purpura. The W.B.C. count was markedly increased in the most cases of sepsis and leukemia, decreased in aplstic anemia, and within normal range in allergic purpura. The platelet count was below 10,000/mm2 in 97% cases of the thrombocytopenic purpura, while within normal range in non-thrombocytopenic purpura. 5) The bleeding time and the clotting time were within normal ranges in most of all cases. The Rumpel-Leede test revealed positive result in 85% cases of I.T.P., while in only 20% of allergic purpura.