J Korean Soc Emerg Med.  2010 Jun;21(3):412-415.

Acute Fatty Liver of Pregnancy Associated with Diabetes Insipidus

Affiliations
  • 1Department of Emergency Medicine, College of Medicine, Chungbuk National University, Cheongju, Korea. drrhec@chungbuk.ac.kr

Abstract

Acute fatty liver of pregnancy (AFLP) is a rare but potentially fatal complication of pregnancy that occurs in the third trimester, and results in microvesicular fat deposition in the liver, resulting in severe hepatic dysfunction. AFLP diagnosis is very difficult because of the low sensitivity of noninvasive radiologic techniques including ultrasound, computed tomography, and magnetic resonance imaging. Hence, one has to take a careful history and do a careful physical examination with laboratory finding for diagnosis of AFLP. Prompt diagnosis and early delivery can greatly decrease maternal and perinatal mortality.

Keyword

Fatty liver; Pregnancy; Free fatty acids

MeSH Terms

Diabetes Insipidus
Fatty Acids, Nonesterified
Fatty Liver
Female
Humans
Liver
Magnetic Resonance Imaging
Perinatal Mortality
Physical Examination
Pregnancy
Pregnancy Complications
Pregnancy Trimester, Third
Fatty Acids, Nonesterified
Fatty Liver
Pregnancy Complications
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