J Korean Soc Emerg Med.  2004 Dec;15(6):580-587.

Aspect and Effect of Sodium Bicarbonate Use in Cardiopulmonary Resuscitation

• Jang HY
• Choi YH
• Park JO
• Eo EK
• Jung KY

Abstract

PURPOSE
Recently, bicarbonate use in cardiopulmonary resuscitation (CPR) has been reappraised in some studies. This study was performed to consider aspects of sodium bicarbonate (SB) use in CPR and to evaluate the effect of SB use in CPR.
METHODS
In a tertiary university hospital, the CPR records of out-of-hospital cardiac arrest (OHCA) patients over a two-year period were reviewed. First, we examined the cardiac arrest variables, whether SB was used or not, and the time when SB was used. Second, we analyzed the effect of SB use on the CPR outcome.
RESULTS
The study included 187 patients. SB was used in 78 patients (42%). The mean time when SB was used was 16 minutes after initiation of CPR, corresponding to an average 38-minute elapsed time from the patient's collapse. There was no relation between the prehospital arrest time and the SB use rate, but a positive relation was seen between the CPR duration and the SB use rate. The investigation of the effect of SB on CPR outcome included 82 patients, and we performed a logistic regression analysis. SB use seemed to be related to return of spontaneous circulation (ROSC), however, statistically, it was not significant (OR=2.499, 95% CI: 0.491, 12.718).
CONCLUSION
SB use for OHCA patient resuscitation was not based on consideration of prehospital hypoxia time. SB use did not affect ROSC in this retrospective study.

Keyword

Sodium bicarbonate; Cardiac arrest; Cardiopulmonary resuscitation

MeSH Terms

Anoxia
Cardiopulmonary Resuscitation*
Heart Arrest
Humans
Logistic Models
Out-of-Hospital Cardiac Arrest
Resuscitation
Retrospective Studies
Sodium Bicarbonate*
Sodium*
Sodium
Sodium Bicarbonate