J Korean Soc Endocrinol.  1997 Dec;12(4):602-608.

A Case of Pituitary Metastasis of Lung Presenting as Diabetes Insipidus

Abstract

This is a case report of a 61 years old man with suprasellar and pituitary metastasis from bronchogenic adenocarcinoma who developed polyuria and polydipsia. The clinical diagnosis has been made by bronchoscopy with washing cytology, biopsy of cervical lymph node, and brain MRI scan. Brain MRI scan showed metastatic tumor in the suprasellar area and pituitary gland with invasion of pituitary stalk. Light microscopic findings revealed adenocarcinoma in bronchoscopic washing cytology, and metastatic adenocarcinoma in the cervical lymph node. The combined pituitary stimulation test showed decreased reserve capacity of anterior pituitary hormones. And the water deprivation test also showed complete central diabetes inspidus. We report a case of suprasellar and pituitary metastasis from bronchogenic adenocarcinoma with a review of the literature.


MeSH Terms

Adenocarcinoma
Biopsy
Brain
Bronchoscopy
Diabetes Insipidus*
Diagnosis
Humans
Hypopituitarism
Lung Neoplasms
Lung*
Lymph Nodes
Magnetic Resonance Imaging
Middle Aged
Neoplasm Metastasis*
Pituitary Gland
Pituitary Hormones, Anterior
Polydipsia
Polyuria
Water Deprivation
Pituitary Hormones, Anterior
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