J Korean Soc Endocrinol.  1997 Jun;12(2):328-337.

A Case of Multiple endocrine neoplasia type 2a

Abstract

Multiple endocrine neoplasia type2a (MEN type2a) is a dominantly inherited cancer syndrome which is characterized by medullary thyroid carcinoma, pheochromocytoma and parathyroid hyperplasia or adenoma. Recent reports show that DNA analysis will be introduced into screening of MEN type2a families. Regular prospective screening and appropriate surgical intervention can reduce the morbidity and mortality due to MEN type2a. We experienced a case of MEN type 2a in a 46-year-old female patient. She had undergone bilateral adrenalectomy due to pheochromocytoma, followed by a total radical thyroidectomy, which revealed medullary thyroid carcinoma of the both thyroid gland and parathyroid hyperplasia.


MeSH Terms

Adenoma
Adrenalectomy
DNA
Female
Humans
Hyperplasia
Male
Mass Screening
Middle Aged
Mortality
Multiple Endocrine Neoplasia Type 2a*
Multiple Endocrine Neoplasia*
Pheochromocytoma
Thyroid Gland
Thyroid Neoplasms
Thyroidectomy
DNA
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