J Korean Child Neurol Soc.  2010 May;18(1):112-116.

A Case of Pediatric Nephrolithiasis Associated with Topiramate Treatment

Affiliations
  • 1Department of Pediatrics, Seoul National University College of Medicine, Seoul, Korea. neuroandy@korea.com
  • 2Seoul National University College of Medicine, Seoul, Korea.

Abstract

Topiramate is an antiepileptic drug widely used to treat various seizures, mood disorders and migraine based on its various pharmacological mechanisms. Even though nephrolithiasis is listed as one of its side effects, there have been no cases reporting nephrolithiasis caused by use of topiramate on Korean pediatric patients. Since the use of topiramate is increasing in many patients, the possibility of nephrolithiasis after the treatment needs to be considered. Here, we report our experience in correcting neprholithiasis by simply discontinuing topiramate without administering any additional treatments.

Keyword

Topiramate; Nephrolithiasis; Antiepileptics; Side effects

MeSH Terms

Anticonvulsants
Fructose
Humans
Migraine Disorders
Mood Disorders
Nephrolithiasis
Seizures
Anticonvulsants
Fructose
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