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Recent Advances in Anti-Obesity Drugs

Son JW

Obesity is a chronic, complex, and heterogeneous disease that is affected by genetic, developmental, biological, and environmental factors; thus, it is necessary to approach obesity with an integrated and comprehensive...
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Anti-Obesity Drugs: Long-Term Efficacy and Safety: An Updated Review

Tak YJ, Lee SY

As a chronic and relapsing disease, obesity negatiⓇvely impacts the health of men to a greater extent than that of women, with a higher risk of cardiovascular disease. Since lifestyle...
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Comprehensive Review of Current and Upcoming Anti-Obesity Drugs

Son JW, Kim S

Obesity is among the leading causes of morbidity and mortality worldwide and its prevalence continues to increase globally. Because obesity is a chronic, complex, and heterogeneous disease influenced by genetic,...
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Current Long-Term Pharmacotherapies for the Management of Obesity

Kim BY, Kang SM, Kang JH, Kim KK, Kim B, Kim SJ, Kim YH, Kim JH, Kim JH, Nam GE, Park JY, Son JW, Shin HJ, Oh TJ, Lee H, Jeon EJ, Chung S, Hong YH, Kim CH, Committee of Clinical Practice Guidelines, Korean Society for the Study of Obesity (KSSO)

Obesity is a serious and growing worldwide health challenge associated with type 2 diabetes mellitus, cardiovascular disease, osteoarthritis, some cancers, sleep apnea, asthma, and nonalcoholic fatty liver. The Korean Society...
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A case of toxic epidermal necrolysis due to topiramate

You SJ, Yoo SJ, Kim HB

Topiramate is an antiepileptic drug effective for multiple types of seizure and is also used to prevent migraine attack. Several side effects have been reported, such as metabolic acidosis, nephrolithiasis,...
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Long-Term Current Management of Enduring Obesity in Diabetes

Kim CH

Obesity increases the risk of diabetes, hypertension, and cardiovascular diseases, ultimately contributing to mortality. The Korean Society for the Study of Obesity (KSSO) was established to improve the management of...
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Bullous Fixed Drug Eruption due to Topiramate

Yim SH, Kim S, Choi CW, Lee Y, Seo YJ, Hong D

  • KMID: 2502307
  • Korean J Dermatol.
  • 2020 Feb;58(2):143-144.
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Effects of Antiepileptic Drugs on Language Abilities in Benign Epilepsy of Childhood with Centrotemporal Spikes

Han MJ, Kim SJ

BACKGROUND AND PURPOSE: This study is to assess the responsiveness of electroencephalography (EEG) abnormalities and their effects on language ability after initiating different types of antiepileptic therapy in children with...
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Reversible Lesion in The splenium of The Corpus Callosum Induced by Topiramate in a Patient with Migraine

Heo D, Lee SK, Park JH, Lee TK

Reversible lesion in the splenium of the corpus callosum in patients with epilepsy is often associated with some antiepileptic drugs. However, topiramate has never been reported as a possible inducer...
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Factors Associated with Favorable Outcome of Topiramate Migraine Prophylaxis in Pediatric Patients

Yoo IH, Kim W, Kim H, Lim BC, Hwang H, Chae JH, Choi J, Kim KJ

BACKGROUND AND PURPOSE: There are few studies that have investigated predictive factors related to migraine prophylaxis of which produced inconsistent results. The aim of this study was to identify factors...
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Effects of low-dose topiramate on language function in children with migraine

Han SA, Yang EJ, Kong Y, Joo CU, Kim SJ

PURPOSE: This study aimed to verify the safety of low-dose topiramate on language development in pediatric patients with migraine. METHODS: Thirty newly diagnosed pediatric patients with migraine who needed topiramate were...
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A New Approach to the Prophylaxis of Cyclic Vomiting: Topiramate

Sezer OB, Sezer T

  • KMID: 2433458
  • J Neurogastroenterol Motil.
  • 2016 Oct;22(4):656-660.
  • doi: 10.5056/jnm16035
BACKGROUND/AIMS: The aim of this study was to compare the efficacy and tolerability of topiramate and propranolol in preventing pediatric cyclic vomiting syndrome. METHODS: A retrospective medical-record review of patients who...
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New Drugs for Obesity Treatment

Kim WJ, Lee CB

There have recently been many advances in obesity treatment, including lifestyle modifications and pharmacological and surgical treatments. Specifically, pharmacological strategies have improved significantly. However, the history of the development of...
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Usefulness of Extracorporeal Treatment for Combined Intoxication with Controlled-Release Carbamazepine and Topiramate

Kim M, Kwon OY, Kim DH, Yoo S, Park DJ, Jeong H, Son S, Kim SK, Kang H, Park KJ, Choi NC, Lim B

Controlled-release carbamazepine (CBZ) could be more harmful than the regular form in special situations due to their respective biochemical characteristics. When primary treatment is not effective in acute intoxication, extracorporeal...
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Safety of Anti-Obesity Drugs Approved for Long-Term Use

Kim KK

Because of the widespread use of ant-obesity medications, bariatricians need to be aware not only of common adverse events but also uncommon serious events in the pharmacotherapy of obesity. Safety...
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The Effectiveness and Tolerability of Topiramate and Lidocaine Add-on Therapy in Children with Refractory Status Epilepticus

Kang BH, Sohn Y, Kim JE, Hwang SK, Kwon S

  • KMID: 2329263
  • J Korean Child Neurol Soc.
  • 2014 Jun;22(2):72-76.
PURPOSE: This study was aimed to compare the effectiveness and tolerability of topiramate add-on therapy versus lidocaine add-on therapy in children with refractory status epilepticus. METHODS: We performed a retrospective analysis...
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Therapeutic Drug Monitoring of Topiramate in Status Epilepticus

Koo DL, Seo S, Kim D, Hong SB, Joo EY, Lee SY

  • KMID: 1431577
  • J Korean Epilepsy Soc.
  • 2013 Jun;17(1):1-7.
PURPOSE: Status epilepticus (SE) is a pathologic state where pharmacokinetic alterations can be more pronounced and more rapid than during the other epileptic states. The consequences of such changes can...
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Low-dose, Once-a-day Treatment of Topiramate in Benign Childhood Epilepsy with Centrotemporal Spikes

Choi YE, Jang HI, Bae SY, Son YJ, Lee YJ, Kim YO, Woo YJ

  • KMID: 1441220
  • J Korean Child Neurol Soc.
  • 2012 Jun;20(2):71-79.
PURPOSE: Benign childhood epilepsy with centrotemporal spikes (BECTS) is known to have a good prognosis, and is easily controlled with antiepileptic drugs. In this study, we evaluate the efficacy of...
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Bone Mineral Density in Ambulatory Epileptic Children with New Antiepileptic Drug Monotherapy

Ko JH, Lee GM, Lee EH, Chung S

  • KMID: 2329481
  • J Korean Child Neurol Soc.
  • 2011 Dec;19(3):184-190.
PURPOSE: This study was conducted for evaluation of the effects of new antiepileptic drugs on bone mineral density in children with epilepsy. METHODS: The study group consisted of 35 age and...
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Short term outcomes of topiramate monotherapy as a first-line treatment in newly diagnosed West syndrome

Lee GM, Lee KS, Lee EH, Chung S

PURPOSE: To investigate the efficacy of topiramate monotherapy in West syndrome prospectively. METHODS: The study population included 28 patients (15 male and 13 female children aged 2 to 18 months) diagnosed...
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