Kosin Med J.  2016 Jun;31(1):5-10. 10.7180/kmj.2016.31.1.5.

Uterine cancer and ezrin expression

Affiliations
  • 1Department of Interdisciplinary Program in Biomedical Science, Soonchunhyang University Graduate School, Asan-si, Chungcheongnam-do, Korea.
  • 2Department of Obstetrics and Gynecology, Soonchunhyang University College of Medicine, Bucheon-si, Gyeonggi-do, Korea. heeobgy@schmc.ac.kr
  • 3Department of Obstetrics and Gynecology, College of Medicine, Kosin University, Busan, Korea.
  • 4Department of Life Science and Biotechnology, Soonchunhyang University College of Natural Sciences, Asan-si, Chungcheongnam-do, Korea.

Abstract

Today, almost 20% of female cancers are gynecological in nature. In particular, uterine cervical cancer and endometrial cancer (which have been intensively studied) seriously compromise female health. One of the ezrin-radixin-moesin (ERM) proteins, ezrin, has been associated with cancer in prior studies, including the two cancers mentioned above. Ezrin expression increases, as does the expression of other factors, in uterine cervical cancer; ezrin may promote cancer development by influencing the actions of the other factors. Also, an increase in ezrin level contributes to the development of diseases such as endometrial cancer.

Keyword

Cervical intraepithelial neoplasia; endometrial neoplasms; neurofibronin 2; uterine cervical neoplasms

MeSH Terms

Cervical Intraepithelial Neoplasia
Endometrial Neoplasms
Female
Humans
Uterine Cervical Neoplasms
Uterine Neoplasms*
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