J Nutr Health.  2015 Apr;48(2):123-132. 10.4163/jnh.2015.48.2.123.

Anti-obesity effect of Korean Hamcho (Salicornia herbacea L.) powder on high-fat diet-induced obese rats

• Kim MJ
• Jun HY
• Kim JH

• KMID: 2327182
• DOI: http://doi.org/10.4163/jnh.2015.48.2.123

Abstract

PURPOSE
The objective of this study was to examine whether Hamcho freeze-dried powder and Hamcho freeze-dried nano powder have an anti-obese effect on high fat diet-induced obese rats.
METHODS
Sprague Dawley rats were divided into 6 different groups, each of which was bred for 8 weeks with a different experimental diet: normal diet group (NC), high fat diet group (HFC), high fat diet + 2% Salicornia herbacea L. freeze-dried powder group (2% HS), high fat diet + 5% Salicornia herbacea L. freeze-dried powder group (5%HS), high fat diet + 1% Salicornia herbacea L. freeze-dried nano powder group (1% HSN), high fat diet + 2% Salicornia herbacea L. freeze-dried nano powder group (2% HSN).
RESULTS
The 5% HS group showed a weight loss effect in body weight, liver and adipose tissue by reducing the amount of dietary intake and food efficiency ratio. In addition, the 5% HS group showed a significant reduction of serum leptin concentration, while having a beneficial effect on the improvement of lipid metabolism such as increase the serum concentration of adiponectin. However, Hamcho freeze-dried nano powder did not show a weight loss effect.
CONCLUSION
Overall data indicated that Hamcho seemed to have anti-obesity effects. In particular, consumption of 5% Hamcho freeze-dried powder might have beneficial effects on body weight, serum adiponectin level, and lipid profiles since it led to reduced body weight and growth of adipose tissues by suppressing dietary intakes. However conduct of further research studies is needed for analysis of active components and biochemical action mechanism of Hamcho.

Keyword

Salicornia herbacea L.; anti-obesity effect; lipid profile; leptin; adiponectin

MeSH Terms

Adiponectin
Adipose Tissue
Animals
Body Weight
Chenopodiaceae
Diet
Diet, High-Fat
Leptin
Lipid Metabolism
Liver
Rats*
Rats, Sprague-Dawley
Weight Loss
Adiponectin
Leptin

Figure

• 

  Fig. 1. Body weight change

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