J Korean Surg Soc.  2000 Aug;59(2):270-274.

Primary Hyperparathyroidism Caused by a Giant Parathyroid Adenoma: A case report

Affiliations
  • 1Department of Surgery, Chonbuk National University College of Medicine.
  • 2Department of Diagnostic Radiology, Chonbuk National University College of Medicine.
  • 3Department of Pathology, Chonbuk National University College of Medicine.

Abstract

Primary hyperparathyroidism is a relatively rare disease entity in Korea. It is characterized by severe skeletal and renal changes due to hypersecretion of parathyroid hormone and rarely shows peptic ulceration, hypertension, pancreatitis and impaired mentality. Primary hyperparathyroidism is most commonly caused by an adenoma, or hyperplasia and rarely by cancer of the parathyroid gland. The authors experienced a case involving a giant parathyroid adenoma in a 62-year-old female. The main symptoms were general weakness, anorexia, and constipation. We detected the giant parathyroid adenoma on the anterior neck by using preoperative localization methods, such as ultrasonography, and a thallium-technetium subtraction scan. A parathyroidectomy was carried out, and the parathyroid adenoma measured 5.0 cm 3.2 cm in size and 12 gm in weight. Clinical laboratory reports and symptoms were normalized with no sequelae. We report this case with a review of the literature related to sizes and weights of adenomas.

Keyword

Primary hyperparathyroidism; Giant adenoma

MeSH Terms

Adenoma
Anorexia
Constipation
Female
Humans
Hyperparathyroidism, Primary*
Hyperplasia
Hypertension
Korea
Middle Aged
Neck
Pancreatitis
Parathyroid Hormone
Parathyroid Neoplasms*
Parathyroidectomy
Peptic Ulcer
Rare Diseases
Ultrasonography
Weights and Measures
Parathyroid Hormone
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