J Korean Surg Soc.  2012 May;82(5):330-334.

Interdigitating dendritic cell sarcoma occured alone in axilla

• Han SW
• Kim ZS
• Kim HM
• Lee J
• Kang GH
• Cho HD
• Kim SY
• Park NK
• Lim CW
• Lee MH

Abstract

Interdigitating dendritic cell sarcoma (IDCS) is a very rare disease around the world and its prognosis is known to be aggressive. This reports a case diagnosed as IDCS of the axillary region treated in Soonchunhyang University Hospital. A 57-year-old female visited Soonchunhyang University Hospital with a left axillary mass. The mass was hard and fixed. Computed tomography observed a 7 cm lymph node at the left axilla, and core biopsy suspected sarcoma. In another study, there was no specific finding except the axillary lesion. Left axillary lymph node dissection (level I, II) was conducted and the pathologic report finally showed IDCS. The patient was treated with only radiotherapy and followed up without recurrence for 13 months up to now. IDCS is a very rare sarcoma that is hard to diagnose and progresses fast. Thus, treatment is very difficult. Proper treatment can be better established after more experiences.

Keyword

Interdigitating dendritic cell sarcoma; Axilla

MeSH Terms

Axilla
Biopsy
Dendritic Cell Sarcoma, Interdigitating
Dendritic Cells
Female
Humans
Lymph Node Excision
Lymph Nodes
Middle Aged
Polyenes
Prognosis
Rare Diseases
Recurrence
Sarcoma
Polyenes

Figure

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  Fig. 1 Axillary lymph node enlargement at computed tomography. (A) Arrow shows about 7 cm sized lymph node. (B) Arrow shows about 2 cm sized lymph node around main.

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  Fig. 2 Positron emission tomography shows increase of 18-fluoro-deoxyglucose in left axillary region.

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  Fig. 3 Microscopic lymph node finding in axillary interdigitating dendritic cell sarcoma (IDCS). (A) Axillary IDCS (H&E, ×400). (B) S-100 protein (immunohistochemical stain, ×400).

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