J Korean Acad Rehabil Med.  2007 Apr;31(2):238-242.

The Effect of Levodopa on Akinetic Mutism in Bilateral Anterior Cerebral Artery Infarction: A case report

Affiliations
  • 1Department and Research Institute of Rehabilitation Medicine, Yonsei University College of Medicine, Korea. presider@hanmail.net

Abstract

Akinetic mutism is a clinical syndrome in which the patient is unable to speak (mutism) or move (akinesia). Various brain lesions can induce akinetic mutism. We attended a 71-year-old woman who presented with akinetic mutism caused by bilateral anterior cerebral artery infarction. The patient improved after the administration of levodopa com-bined with carbidopa, in response to visual and verbal stimuli. Increased verbal output and spontaneous motor activities were also noted. Levodopa may be helpful to the treatment of akinetic mutism.

Keyword

Akinetic mutism; Anterior cerebral artery infarction; Levodopa

MeSH Terms

Aged
Akinetic Mutism*
Anterior Cerebral Artery*
Brain
Carbidopa
Female
Humans
Infarction, Anterior Cerebral Artery*
Levodopa*
Motor Activity
Carbidopa
Levodopa
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