J Korean Soc Pediatr Nephrol.
2009 Oct;13(2):176-188.
Current Status of Children on Peritoneal Dialysis in Korea: A Cross-Sectional Multicenter Study
- Affiliations
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- 1Department of Pediatrics, University of Ulsan, College of Medicine Asan Medical Center, Seoul, Korea. pedkid@gmail.com
- 2Department of Pediatrics, College of Medicine, Korea University, Seoul, Korea.
- 3Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
- 4Department of Pediatrics, Seoul National University Childrens Hospital, Seoul, Korea.
Abstract
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PURPOSE: Peritoneal dialysis (PD) is the major form of dialysis in use for infants and children with end-stage renal disease (ESRD). The aim of this study was to gain insight into the current status of children on PD in Korea.
METHODS
In May 2008, questionnaires were sent to the pediatric nephrologists via e-mail. Four centers replied and those data were reviewed.
RESULTS
A total of 103 patients were included in this study. Male to female ratio was 1.6:1. Mean age was 11.5+/-4.9 years (0-19 years). Primary renal diseases diagnosed were as follows: primary glomerular disease (34%), chronic pyelonephritis-reflux nephropathy (14.6%), systemic disease (9.7%), renal hypoplasia/dysplasia (8.7%), heredofamilial disease (6.8%), vascular disease (3.9%), drug-induced nephropathy (1.0%), and unknown (12.6%). PD modalities were as follows: CAPD (42.7%), CCPD (27.2%), NIPD (11.7%), and Hybrid (18.4%). Weekly total Kt/V was 2.1+/-0.7 (0.3- 4.1). Results of peritoneal equilibrium test were as follows: low 36.8%, low average 31.6%, high average 19.7%, and high 11.8%. Z-score for weight was -1.00+/-1.20 (-4.54~+2.50). Z-score for height was -1.55+/-1.65 (-9.42~+1.87). Growth hormone was administered in 24.3% of patients. Anti-hypertensive drugs were administered in 64.0% of patients. Laboratory findings were as follows: hemoglobin 10.5+/-1.4 g/dL, calcium 9.7+/-0.7 mg/dL, phosphorus 5.4+/-1.4 mg/dL, and parathyroid hormone 324.2+/-342.8 pg/mL.
CONCLUSION
Primary glomerular disease was the most common cause of ESRD. CAPD was the most prevalent PD modality. Low and low average peritoneal transport type were common. Growth disturbance were noted in many patients. Some patients had hypertension even with anti- hypertensive drugs. Calcium-phosphorus levels were maintained adequately, but many patients had secondary hyperparathyroidism.