J Korean Soc Pediatr Nephrol.
2001 Apr;5(1):51-58.
Therapeutic Effect of Nocturnal Water Restriction in Children with Primary Nocturnal Enuresis
- Affiliations
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- 1Department of Pediatrics, College of Medicine, Ewha Womans University, Seoul, Korea.
Abstract
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PURPOSE : Treatment of primary nocturnal enuresis (PNE) includs folk remedies and various treatments based on
pathogenesis. We assessed the therapeutic effect of nocturnal water restriction as the primary treatment of PNE.
MATERIALS AND METHODS
: From October 1998 to June 1999, 41 children with PNE (>3 wet nights per week)
who visited Ewha Womans University Mokdong hospital and who had good compliances to nocturnal water restriction
for 2 months were included. Before and during nocturnal water restriction, daily fluid intake and urine volume were
recorded for 2 days every 2 weeks. Responses to nocturnal water restriction were classified according to the decrease of
wet nights as complete (>90%), partial (50-90%) and no (<50%) response. Predictors such as age, sex, daytime
voiding dysfunction, fluid intake, urine volume, maximum urine volume per void and fasting urine osmolality were
evaluated.
RESULTS
: The response rate to nocturnal water restriction for 2 month was 82.9% (34/41) [complete response :
39.0% (16/41), partial response : 43.9% (18/41)]. The response rate to nocturnal water restriction was significantly
higher in monosymptomatic PNE than polysymptomatic PNE and more effective in PNE with er nocturnal fluid
intake, nocturnal urine volume, and maximum urine volume than lower nocturnal fluid intake, nocturnal urine volume
and maximum urine volume per void (p<0.05). Nocturnal urine volume, maximum urine volume per void and fasting
urine osmolality after nocturnal water restriction has significantly increased higher in complete response and partial
response group than in no response group (p<0.05).
CONCLUSION
: The nocturnal water restriction was effective in monosymptomatic PNE with nocturnal polydypsia,
nocturnal polyuria and high bladder capacity.