J Korean Soc Pediatr Nephrol.  2012 Oct;16(2):126-131.

A Pediatric Case of Primary Sjogren's Syndrome Associated with Nephrogenic Diabetes Insipidus and Renal Tubular Acidosis

Affiliations
  • 1Department of Pediatrics, The Catholic University of Korea, College of Medicine, Seoul, Korea. nicedoc@catholic.ac.kr

Abstract

Sjogren's syndrome (SS) is an autoimmune disorder primarily affecting the salivary and lacrimal glands. In addition, extra-glandular manifestations involving the lungs, liver, kidneys, pancreas, skin and central nervous system were reported in patients with SS. These extra-glandular manifestations are not rare in adult patient, but are very rare in pediatric SS. Renal manifestations are relatively common in adult SS, but are rarely reported in childhood SS. We experienced a girl with primary SS manifested with nephrogenic diabetes insipidus and renal tubular acidosis.

Keyword

Sjogren's syndrome; Diabetes insipidus; Renal tubular acidosis; Child

MeSH Terms

Acidosis, Renal Tubular
Adult
Central Nervous System
Child
Diabetes Insipidus
Diabetes Insipidus, Nephrogenic
Humans
Kidney
Lacrimal Apparatus
Liver
Lung
Pancreas
Sjogren's Syndrome
Skin
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