Yeungnam Univ J Med.  2014 Jun;31(1):61-64.

Panhypopituitarism due to craniopharyngioma with bilateral slipped capital femoral epiphysis

• Kim SW
• Song YJ
• Choi EJ
• Han DH
• Jung HY
• Yu SH
• Yoo HJ
• Yu JM

Abstract

Craniopharyngiomas are rare primary intracranial tumors. Despite their benign histological appearance, they are often associated with an unfavorable prognosis. The typical manifestations upon diagnosis are headache, visual impairment, polyuria/polydypsia, growth retardation, disturbance of pubertal development, and significant weight gain. The treatment options include radical surgery or radiotherapy, or a combination of these modalities. Slipped capital femoral epiphysis (SCFE) is the most common adolescent hip disorder. SCFE occurs when the capital femoral epiphysis displaces posteriorly on the femoral neck at the level of the physis. The etiology of SCFE is thought to be multifactorial and may include obesity, growth surges, and less common endocrine disorders. The related endocrine disorders include hypothyroidism, growth hormone supplementation, hypogonadism, and panhypopituitarism. Reported herein is a case of panhypopituitarism caused by craniopharyngioma combined with SCFE.

Keyword

Hypopituitarism; Craniopharyngioma; Slipped capital femoral epiphysis

MeSH Terms

Adolescent
Craniopharyngioma*
Diagnosis
Epiphyses
Femur Neck
Growth Hormone
Headache
Hip
Humans
Hypogonadism
Hypopituitarism
Hypothyroidism
Obesity
Prognosis
Radiotherapy
Slipped Capital Femoral Epiphyses*
Vision Disorders
Weight Gain
Growth Hormone