Tuberc Respir Dis.  2012 Jun;72(6):507-510.

Intralobar Pulmonary Sequestration Showing Increased Serum CA19-9

• Ahn YH
• Song MJ
• Park SH

Abstract

Carbohydrate antigen 19-9 (CA19-9) is a specific tumor marker of the biliary, pancreatic and gastrointestinal tracts. CA19-9 is occasionally elevated in serum in patiens with benign pulmonary diseases such as bronchiectasis, idiopathic interstitial pneumonia or collagen disease-associated pulmonary fibrosis. Intralobar pulmonary sequestration is an uncommon congenital lung anomaly. It is dissociated from the normal tracheobronchial tree and is supplied by an anomalous systemic artery. There have been some reports of elevation of CA19-9 in this lesion. We report a case of intralobar pulmonary sequestration with elevated serum CA19-9 in a 29-year-old man who was diagnosed with bronchiectasia of left lower lung field on general check up. He had no evidence of any malignant disease in pancreatobiliary or gastrointestinal tracts. Elevated serum CA19-9 level might be encountered with benign pulmonary disease such as pulmonary sequestration.

Keyword

Bronchopulmonary Sequestration; CA-19-9 Antigen

MeSH Terms

Adult
Arteries
Bronchiectasis
Bronchopulmonary Sequestration
CA-19-9 Antigen
Collagen
Gastrointestinal Tract
Humans
Idiopathic Interstitial Pneumonias
Lung
Lung Diseases
Pulmonary Fibrosis
CA-19-9 Antigen
Collagen

Figure

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  Figure 1 High-resolution computed tomography scan shows emphysematous change (double arrow) and bronchiectasis (arrow) in left lower lobe of lung.

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  Figure 2 Contrast enhanced computed tomography demonstrates an anomalous artery (arrow) originating from the upper abdominal aorta and extending into the sequestered lung (double arrow).

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  Figure 3 Volume rendering image demonstrates an artery (arrow) originating from the descending aorta and supplying the intralobar pulmonary sequestration. Also note a large draining vein (double arrow) originating from the sequestration and draining into the left inferior pulmonary vein.

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