Tuberc Respir Dis.  2011 Dec;71(6):431-437.

The Application of Impulse Oscillometry (IOS) in the Workers Who had been Exposed to Inorganic Dust Induced Early Airway Obstruction

• Lee JO
• Lee YL
• Choi BS
• Lee HK

Abstract

BACKGROUND
We tried to examine the small airway diseases which can be found early, in workers exposed to inorganic dusts. This is measured in normal breath by using the impulse oscillometry (IOS).
METHODS
The Pulmonary function test (forced vital capacit [FVC], forced expiratory volume in one second [FEV1], forced expiratory flow between 25% and 75% of vital capacity [FEF25-75]), IOS resistance (Rrs at 5, 10, 15, 20, 25, 35 Hz) and reactance (Xrs at 5, 10, 15, 20, 25, 35 Hz) were measured for 454 workers. The subjects were classified into 173 workers of normal (38.1%) and 281 patients with pneumoconiosis (61.9%).
RESULTS
There were significant differences between normal and patients with FVC (3.82+/-0.61 vs. 3.53+/-0.56 L), FEV1 (2.67+/-0.63 vs. 2.35+/-0.48 L), and FEF25-75 (1.88+/-0.95 vs. 1.47+/-0.80 L/sec) between groups (p<0.05). And as for IOS, there was no significant difference in resistance (Rrs) (p>0.05), and there were significant differences between normal and patients with reactance (Xrs) 15 Hz (0.003+/-0.05 vs. -0.006+/-0.04 kPa/L/s), 20 Hz (0.043+/-0.05 vs. 0.031+/-0.04 kPa/L/s), and 35 Hz (0.141+/-0.05 vs. 0.131+/-0.05 kPa/L/s) between groups (p<0.05).
CONCLUSION
We could find out that 15 Hz, 20 Hz, and 35 Hz values of reactance were significantly influenced by pneumoconiosis. When usefulness and reproducibility to carry out the IOS are considered, it is thought that in future work will be required to draw the reference values for normal Korean persons.

Keyword

Respiratory Function Tests; Airway Obstruction

MeSH Terms

Airway Obstruction
Dust
Forced Expiratory Volume
Humans
Oscillometry
Pneumoconiosis
Reference Values
Respiratory Function Tests
Vital Capacity
Dust

Figure

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  Figure 1 Comparison of resistance parameters between the control and Pneumoconiosis group (p>0.05). Rrs: resistance.

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  Figure 2 Comparison of reactance parameters between the control and Pneumoconiosis group. Xrs: reactance.

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