Tuberc Respir Dis.  2001 Aug;51(2):178-183. 10.4046/trd.2001.51.2.178.

A Case of the Membranous Glomerulonephritis Associated with Squamous Cell Lung Cancer

• Cho YL
• Seo YJ
• Kim MG
• Lee JY
• Jung SH
• Ryoo HM
• Yeun HD
• Lee IH
• Ahn KS
• Sin TL
• Hyun DS
• Lee SC
• Cho CH

• KMID: 2318351
• DOI: http://doi.org/10.4046/trd.2001.51.2.178

Abstract

The nephrotic syndrome that occurs in the absence of renal vein thrombosis, amyloidosis, neoplastic infiltration of the kidneys is an unusual but a well recognized paraneoplastic syndrome. The most frequently reported neoplasms associated with nephrotic syndrome are Hodgkin's disease and various carcinomas. The most common renal lesions are membranous glomerulonephritis(MGN) associated with carcinomas and minimal change lesions associated with Hodgkin's disease. Approximately 40% to 45% of patients clinically manifest the MGN symptoms prior to the diagnosis of the tumor, 40% simultaneously with the tumor and the remaining 15% to 20% following the tumor. Therefore, evaluating the underlying malignancy in patients with MGN is important. Here we report a patient with squamous cell lung cancer, which was detected 12 months after a MGN had been diagnosed, with a review of the relevant literature.

Keyword

Squamous cell lung cancer; Nephrotic syndrome; Menbranous glomerulonephritis(MGN)

MeSH Terms

Amyloidosis
Diagnosis
Glomerulonephritis, Membranous*
Hodgkin Disease
Humans
Kidney
Lung Neoplasms*
Lung*
Nephrotic Syndrome
Paraneoplastic Syndromes
Renal Veins
Thrombosis