Tuberc Respir Dis.
2000 Jan;48(1):14-23.
Preoperative Evaluation for the Prediction of Postoperative Mortality and Morbidity in Lung Cancer Candidates with Impaired Lung Function
- Affiliations
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- 1Department of Internal Medicine, Gachon Medical School, Gil Medical Center, Korea.
- 2Division of Pulmonary and Critical Care Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
- 3Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Abstract
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BACKGROUND: The evaluation of candidates for successful lung resection is important. We studied to Our study was conducted to determine the preoperative predictors of postoperative mortality
and morbidity in lung cancer patients with impaired lung function.
METHOD: Between October 1, 1995 to August 31, 1997, 36 lung
resection candidates with FEV1 of less than 2L or 60% predicted
due to lung cancer were included prospectively. Age, sex, weight
loss, hematocrit, serum albumin, EKG and concomitant illness were
considered as systemic potential predictors for a successful lung
resection. Smoking history, presence of pneumonia, dyspnea scale(1 to 4),
arterial blood gas analysis with room air breathing, routine
pulmonary function test were also included for the analysis.
In addition, predicted postoperative(ppo)pulmonary factors such as
ppo-FEV1, ppo-diffusing capacity(DLco), predicted postoperative
product(PPP) of ppo-FEV1% x ppo-DLco% and ppo-maximal O2
uptake(VO2max) were also measured.
RESULTS
There were 31 men and 5 women with the median age of 65 years
(range 44 to 82) and a mean FEV1 of 1.78 +/-0.06L. Pneumonectomy was
performed in 14 patients, bilobectomy in 8, lobectomy in 14.
Pulmonary complications developed in 10 patients, cardiac complications
in 3, other complications (empyema, air leak, bleeding) in 4. Twelve
patients were managed in the intensive care unit for more than 48 hours.
Two patients died within 30 days after operation. The ppo-VO2max was
less than 10 mg/kg/min in these two patients. MVV was the only predictor
for the pulmonary complications. However, there was no predictors for
the post operative death in this study.