Tuberc Respir Dis.  1998 Apr;45(2):465-469.

Diffuse Pulmonary Infiltration Rapidly Progressed after the Chemotherapy of a Patient with Malignant Lymphoma

Affiliations
  • 1Department of Internal Medicine, Radiology, and Patholgy, College of Medicine, Hanyang University, Seoul, Korea.

Abstract

Acute respiratory failure with diffuse pulmonary infiltration was occurred in a patient with malignant lymphoma 1month after the 8th CHOP chemotherapy. The ground glass and consolidation appearances on chest C-T in this immunodeficient patient could be presented in many clinical situations such as pneumonia by opportunistic infections(fungal, parasites, viral, and usual bacterial pathogens), anti-tumor drug's pulmonary toxicity and tumor invasion. And the other diseases of acute interstitial pneumonitis, alveolar proteinosis, BOOP, pulmonary edema and alveolar hemorrhage, which could present the same radiological findings, should included in differential diagnosis. This patient was diagnosed as the opportunistic pneumonia by Pneumocystis carinii and probably Cytomegalovirus through bronchoalveolar lavage and transbronchial lung biopsy.

Keyword

Opportunistic pneumonia; Pneumocystis carinii(PCP); Cytomegalovirus(CMV); Lymphoma; Chemotherapy; CHOP

MeSH Terms

Biopsy
Bronchoalveolar Lavage
Cryptogenic Organizing Pneumonia
Cytomegalovirus
Diagnosis, Differential
Drug Therapy*
Glass
Hemorrhage
Humans
Lung
Lung Diseases, Interstitial
Lymphoma*
Parasites
Pneumocystis carinii
Pneumonia
Pulmonary Edema
Respiratory Insufficiency
Thorax
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