Soonchunhyang Med Sci.  2011 Dec;17(2):138-142.

A Case of Multiple Liver Metastasis of True Gastric Leiomyosarcoma after Complete Surgical Resection

Affiliations
  • 1Department of Internal Medicine, Soonchunhyang University Cheonan Hospital, Soonchunhyang University College of Medicine, Cheonan, Korea. cklee92@paran.com
  • 2Department of Pathology, Soonchunhyang University Cheonan Hospital, Soonchunhyang University College of Medicine, Cheonan, Korea.

Abstract

Primary leiomyosarcomas of the stomach are very rare tumors originating from mesenchymal tissues and account for only 1% of all malignant gastric neoplasm. We present here a case of primary gastric leiomyosarcoma in a 79-year-old man who presented with a 10 day history of epigastric pain and gastric subepithelial tumor. Endoscopic examination showed a 5 cm in diameter, subepithelial tumor located in the body of the stomach. Radiological investigations showed nonspecific findings except for the primary gastric lesion. Complete histological evaluation including immnuohistochemical staining after complete surgical resection revealed a true leiomyosarcoma of the stomach. One year later, the patient presented with dyspepsia. Endoscopic and radiological evaluation showed a recurrent leiomyosarcoma with multiple liver metastases. Our experience suggests that a careful clinical follow-up after surgical resection should be recommended in patients with gastric leiomyosarcomas because of their aggressive clinical behavior.

Keyword

Leiomyosarcoma; Stomach neoplasms; Neoplasm metastasis; Immnunohistochemistry

MeSH Terms

Aged
Benzeneacetamides
Dyspepsia
Follow-Up Studies
Humans
Leiomyosarcoma
Liver
Neoplasm Metastasis
Piperidones
Stomach
Stomach Neoplasms
Benzeneacetamides
Piperidones
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