Psychiatry Investig.  2015 Jul;12(3):397-401. 10.4306/pi.2015.12.3.397.

Multivariate Analysis of Relationship between Childhood Trauma and Psychotic Symptoms in Patients with Schizophrenia

• Chae S
• Sim M
• Lim M
• Na J
• Kim D

• KMID: 2316502
• DOI: http://doi.org/10.4306/pi.2015.12.3.397

Abstract

The aim of this study was to examine the relationship between childhood trauma and psychotic symptoms in schizophrenic patients after controlling for the possible confounding factors, such as depression and dissociative symptoms. Ninety-eight schizophrenic inpatients participated. Childhood trauma was examined using the Childhood Trauma Questionnaires (CTQ), which consists of physical abuse (PA), sexual abuse (SA), emotional abuse (EA), physical neglect (PN), and emotional neglect (EN). Positive and Negative Syndrome Scale (PANSS), Dissociative Experience Scale (DES), and Beck's Depression Inventory (BDI) were also administered. Data were analyzed by partial correlation and general linear model. The total score of CTQ was positively correlated with positive, general, and total scores of PANSS. All five types of childhood trauma were associated with dissociative symptoms. EA and EN were positively correlated with depressive symptoms. Only SA significantly predicted positive symptoms of schizophrenia after controlling for age, sex, BDI, and DES scores, with a dose-response relationship between SA and positive symptoms.

Keyword

Childhood trauma; Positive symptom; Sexual abuse; Schizophrenia

MeSH Terms

Depression
Humans
Inpatients
Linear Models
Multivariate Analysis*
Surveys and Questionnaires
Schizophrenia*
Sex Offenses