Psychiatry Investig.
2014 Jan;11(1):1-11.
Korean Medication Algorithm for Depressive Disorder: Comparisons with Other Treatment Guidelines
- Affiliations
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- 1Department of Psychiatry, Yeouido St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea. wmbahk@catholic.ac.kr
- 2Department of Psychiatry, Ilsan Paik Hospital, College of Medicine, Inje University, Goyang, Republic of Korea.
- 3Department of Psychiatry, Seoul National Hospital, Seoul, Republic of Korea.
- 4Department of Psychiatry, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Suwon, Republic of Korea.
- 5Department of Psychiatry, School of Medicine, Konkuk University, Chungju, Republic of Korea.
- 6Shinsegae Hospital, Gimje, Republic of Korea.
- 7Namwon Sungil Mental Hospital, Namwon, Republic of Korea.
- 8Department of Psychiatry, Stress Research Institute, Inje University College of Medicine, Seoul Paik Hospital, Seoul, Republic of Korea.
- 9Department of Psychiatry, College of Medicine, Hallym University, Anyang, Republic of Korea.
- 10Department of Psychiatry, College of Medicine, University of Ulsan, Seoul, Republic of Korea.
- 11Department of Psychiatry, College of Medicine, Chung-Ang University, Seoul, Republic of Korea.
Abstract
- We aimed to compare the recommendations of the Korean Medication Algorithm Project for Depressive Disorder 2012 (KMAP-DD 2012) with other recently published treatment guidelines for depressive disorder. We reviewed a total of five recently published global treatment guidelines and compared each treatment recommendation of the KMAP-DD 2012 with those in other guidelines. For initial treatment recommendations, there were no significant major differences across guidelines. However, in the case of nonresponse or incomplete response to initial treatment, the second recommended treatment step varied across guidelines. For maintenance therapy, medication dose and duration differed among treatment guidelines. Further, there were several discrepancies in the recommendations for each subtype of depressive disorder across guidelines. For treatment in special populations, there were no significant differences in overall recommendations. This comparison identifies that, by and large, the treatment recommendations of the KMAP-DD 2012 are similar to those of other treatment guidelines and reflect current changes in prescription pattern for depression based on accumulated research data. Further studies will be needed to address several issues identified in our review.
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