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Suicidal Thinking Among Patients With Spinal Conditions in South Korea: A Population-Based Cross-Sectional Study

Oh TK, Park HY, Song IA

Objective Chronic pain increases the risk of suicide because it is often accompanied by depressive symptoms. However, the existing information regarding suicidal thinking in patients with chronic pain such as...
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Which Severe Mental Illnesses Most Increase the Risk of Developing Dementia? Comparing the Risk of Dementia in Patients with Schizophrenia, Major Depressive Disorder and Bipolar Disorder

Chang WH, Su CC, Chen KC, Hsiao YY, Chen PS, Yang YK

  • KMID: 2545808
  • Clin Psychopharmacol Neurosci.
  • 2023 Aug;21(3):478-487.
  • doi: 10.9758/cpn.22.991
Objective: Previous studies have shown that certain severe mental illnesses (SMIs) increase the risk of dementia, but those that increase the risk to a greater degree in comparison with other...
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Anhedonia and Depressive Disorders

Serretti A

  • KMID: 2545801
  • Clin Psychopharmacol Neurosci.
  • 2023 Aug;21(3):401-409.
  • doi: 10.9758/cpn.23.1086
Anhedonia is a core symptom of depression and of several psychiatric disorders. Anhedonia has however expanded from its original definition to encompass a spectrum of reward processing deficits that received...
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Association between Depression and Mortality in Patients with Pain Conditions: A South Korean Nationwide Cohort Study

Oh TK, Park HY, Song IA

Purpose: Patients with pain conditions may experience depression that greatly complicates treatment. In this study, we examined risk factors for depression in patients with pain conditions and associations between depression...
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Radiomics; A Potential Next “Omics” in Psychiatric Disorders; An Introduction

Alizadeh M, Tanwar M, Sarrami AH, Shahidi R, Singhal A, Sotoudeh H

Psychiatric disorders remain one of the most debilitating conditions; however, most patients are never diagnosed and do not seek treatment. Despite its massive burden on modern society and the health...
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The Impact of N-acetylcysteine on Major Depression: Qualitative Observation and Mixed Methods Analysis of Participant Change during a 12-week Randomised Controlled Trial

Russell SE, Skvarc DR, Mohebbi M, Camfield D, Byrne LK, Turner A, Ashton MM, Berk M, Dodd S, Malhi GS, Cotton SM, Bush AI, Dean OM

Objective: N -acetylcysteine (NAC) is a novel therapeutic agent with multiple mechanisms of action in the central nervous system and a favourable side effect profile. Clinical evidence indicates that adjunctive...
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Multiple Complement Pathway-related Proteins Might Regulate Immunopathogenesis of Major Depressive Disorder

Reddy PV, Talukdar PM, Subbanna M, Bhargav PH, Arasappa R, Venkatasubramanian G, Muralidharan K, Debnath M

Objective: Exacerbated inflammatory pathway has emerged as a predominant etiological construct of major depressive disorder (MDD). Innate immune molecules like complement proteins induce inflammatory responses and also regulate key neurobiological...
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Impaired Cholesterol Metabolism, Neurons, and Neuropsychiatric Disorders

Cheon SY

Cholesterol metabolism plays an essential role in cellular functions (including as a component of the plasma membrane, as an energy source, and in hormone production) under normal conditions. Dysregulated cholesterol...
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Adherence to Antidepressants in Korean Elderly Patients with Major Depressive Disorder

Lee KJ, Lee YJ

Objective: Adherence is an important component in the treatment of various diseases, and poor adherence to antidepressants in patients with major depressive disorder is ...
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Childhood Sexual Abuse and Cortical Thinning in Adults With Major Depressive Disorder

Kim J, Lee C, Kang Y, Kang W, Kim A, Tae WS, Ham BJ, Chang J, Han KM

Objective A growing body of evidence reports on the effect of different types of childhood abuse on the structural and functional architecture of the brain. In the present study, we...
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How the COVID-19 Pandemic Affects the Mental Health of University Hospital Nurses?: Focusing on Resilience, Stress, Depression, Anxiety, and Sleep

Son H, Kim B

Objectives This study aimed to explore how the coronavirus disease-2019 (COVID-19) pandemic affected the mental health of university hospital nurses with a focus on their resilience, stress, depression, anxiety, and...
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Brain-derived Neurotrophic Factor and High Sensitive C-reactive Protein in Bipolar Depression and Unipolar Depression: The Practical Usage as a Discriminatory Tool

Shahyad S, Kheirabadi GR, Jahromi GP, Massaly M

Objective: Brain-derived neurotrophic factor (BDNF) and high sensitive C-reactive protein (hs-CRP) have been reported to play roles in depression and bipolar disorder (BD). However, the probable discriminatory properties of these...
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The effects of diabetes knowledge, self-efficacy, and depression on self-management in older patients with diabetes in the community: A cross-sectional study

Park HG, Kwon MJ

Purpose: The purpose of this study was to identify factors related to self-management of older patients with diabetes. Methods: The subjects of the study were 255 older patients with diabetes...
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Hydroxychloroquine, Interleukin-6 Receptor Antagonists and Corticoid Treatments of Acute COVID-19 Infection: Psychiatric Symptoms and Mental Disorders 4 Months Later

Gasnier M, Choucha W, Montani D, Noël N, Verstuyft C, Radiguer F, Monnet X, Becquemont L, Corruble E, Colle R, on behalf of the COMEBAC Study Group

Objective: Psychiatric symptoms and mental disorders are common after Coronavirus Disease-19 (COVID-19). Some drugs used to treat acute COVID-19 have psychiatric side effects. We assessed the psychiatric symptoms and mental...
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Botulinum Toxin in Facial Aesthetics Affects the Emotion Process: A Meta-analysis of Randomized Controlled Trials

Costa ACdF, Silva ECd, Gondim DV

This study aimed to conduct a meta-analysis of randomized controlled trials (RCTs) to evaluate the effects of the btulinum toxin-A (BT-A) in patiets with mood disorders. PubMed, Scopus, Web of...
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Clinical Utility of Fluid Biomarker in Depressive Disorder

Serretti A

Major depressive disorders are ranked as the single largest contributor to non-fatal health loss and biomarkers could largely improve our routine clinical activity by predicting disease course and guiding treatment....
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The Difference of Cognitive Function in Posttraumatic Stress Disorder and Major Depressive Disorder According to Severity of Symptom

Park C, Gim MS

Objectives This study compared cognitive functions according to the detailed symptoms and severity of posttraumatic stress disorder (PTSD) and major depressive disorder (MDD) and evaluated the relationship between the characteristics...
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Associations among Alzheimer disease, depressive disorder, and risk of end-stage kidney disease in elderly people

Kang SC, Koh HB, Kim HW, Joo YS, Han SH, Yoo TH, Kang SW, Park JT

Background: Alzheimer disease (AD) and depressive disorder (DD) are prevalent among elderly end-stage kidney disease (ESKD) patients. However, whether preexisting mental health disorders increase the risk of ESKD is not...
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Reduced Sulcal Depth in Central Sulcus of Major Depressive Disorder

Shin SJ, Kim A, Han KM, Tae WS, Ham BJ

  • KMID: 2535066
  • Exp Neurobiol.
  • 2022 Oct;31(5):353-360.
  • doi: 10.5607/en22031
Major depressive disorder (MDD) is one of the most common psychiatric disorders, and present various symptoms such as the dysregulation of mood, cognition, and behavior. The purpose of the present...
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Clinical Factors Related to Change of Depression Severity in Major Depressive Disorder Through Index Electroconvulsive Therapy

Yang JW, Kim YT, Kim HC, Jung SW, Lee H

  • KMID: 2534714
  • J Korean Soc Biol Ther Psychiatry.
  • 2022 Oct;28(3):98-108.
Objectives:The aim of this study was to investigate the factors associated with changes in depression severity in index electroconvulsive therapy (ECT) for major depressive disorder. Methods:A retrospective analysis was performed on...
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