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Communication at the End of Life

Onishi H

End-of-life patients experience physical, mental, social, and existential distress. While medical personnel provide medication and care to alleviate patients’ distress, listening to and interacting with patients remains essential for understanding...
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Korean Medication Algorithm Project for Depressive Disorder 2021 (III): Child and Adolescent

Yang CM, Shim SH, Bahk WM, Woo YS, Jeong JH, Wang SM, Kim W, Seo JS, Lee JG, Park YM, Jang SH, Jung MH, Sung HM, Choo IH, Yoon BH, Lee SY, Jon DI, Min KJ

Objectives The Korean Medication Algorithm Project for Depressive Disorder 2021 (KMAP-DD 2021) was a revision of previous works. The main purpose of the current study was to amend guidelines for...
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Korean Medication Algorithm Project for Depressive Disorder 2021 (II): The Subtypes of Depression

Park YM, Seo JS, Woo YS, Bahk WM, Kim W, Jeong JH, Shim SH, Lee JG, Jang SH, Wang SM, Jung MH, Sung HM, Choo LH, Yoon BH, Lee SY, Jon DI, Min KJ

Objectives The Korean Medication Algorithm Project for Depressive Disorder (KMAP-DD) was developed in 2002 and revised in 2006, 2012, 2017. In 2021, the fifth edition was published. This edition reflected new...
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Korean Medication Algorithm Project for Depressive Disorder 2021 (I): Treatment Strategies for Major Depressive Episode

Woo YS, Bahk WM, Seo JS, Park YM, Kim W, Jeong JH, Shim SH, Lee JG, Jang SH, Wang SM, Jung MH, Sung HM, Choo IH, Yoon BH, Lee SY, Jon DI, Min KJ

Objectives The Korean Medication Algorithm Project for Depressive Disorder (KMAP-DD) is a consensus-based medication guideline. To reflect advances in pharmacotherapy for depressive disorders, we have undertaken a fourth revision of...
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White Matter Alterations Associated with Pro-inflammatory Cytokines in Patients with Major Depressive Disorder

Lim J, Sohn H, Kwon MS, Kim B

Objective: Regarding the neuroinflammatory theory of major depressive disorder (MDD), little is known about the effect of pro-inflammatory cytokines on white matter (WM) changes in MDD. We aimed to investigate...
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Does the Loudness Dependence of Auditory Evoked Potential Predict Response to Selective Serotonin Reuptake Inhibitors?: A Meta-analysis

Yoon S, Kim Y, Lee SH

Objective: Loudness of dependence of the auditory evoked potential (LDAEP) is an electroencephalogram-based measure that represents amplitude changes of auditory evoked potentials in primary auditory cortex. Several narrative reviews argued...
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Additional Reduction of Residual Symptoms with Aripiprazole Augmentation in the Patients with Partially Remitted Major Depressive Disorder

Shin C, Pae CU, Kwak KP, Jeon SW, Jeong HG, Kim JW, Lee YJ, Patkar AA, Han C

Objective: Many patients with major depressive disorder (MDD) suffer from residual symptoms without achieving remission. However, pharmacologic options for residual symptoms of MDD have been limited. This study aimed to...
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The Burden of Agoraphobia in Worsening Quality of Life in a Community Survey in Italy

Preti A, Piras M, Cossu G, Pintus E, Pintus M, Kalcev G, Cabras F, Moro MF, Romano F, Balestrieri M, Caraci F, Dell’Osso L, Sciascio GD, Drago F, Hardoy MC, Roncone R, Faravelli C, Musu M, Finco G, Nardi AE, Carta MG

Objective Current nosology redefined agoraphobia as an autonomous diagnosis distinct from panic disorder. We investigated the lifetime prevalence of agoraphobia, its association with other mental disorders, and its impact on...
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A Network Model of Positive Resources, Temperament, Childhood Trauma, and Comorbid Symptoms for Patient with Depressive Disorders

Huh HJ, Lee SY, Lee SS, Chae JH

Objective Temperament, positive resources, childhood trauma, and other clinical comorbid symptoms are related to depressive symptom severity. Here, we used network analysis to examine the interrelations between these clinical factors...
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Is Job Insecurity Worse for Mental Health Than Having a Part-time Job in Canada?

Kim IH, Choi CC, Urbanoski K, Park J, Kim J

Objectives: A growing number of people depend on flexible employment, characterized by outsider employment status and perceived job insecurity. This study investigated whether there was a synergistic effect of employment...
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A Practical Utility and Benefit of Pharmacogenetic-based Antidepressant Treatment Strategy for Major Depressive Disorder Patients with Difficult-to-treat

Lee KH, Bahk WM, Lee SJ, Serretti A, Pae CU

Objective: We report the results of pharmacogenomics-based antidepressant treatment (PGXt) results in treating treatment-resistant major depressive disorder (TRD) patients in real practice. Methods: Nine patients were prescribed NeuropharmagenⓇ for selection of...
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Rapid Symptom Improvement in Major Depressive Disorder Using Accelerated Repetitive Transcranial Magnetic Stimulation

Kim SJ, Son SJ, Jang M, Kim BH, Hong SJ, Seo L, Choi SW, Seok JH, Noh JS

Objective: Repetitive transcranial magnetic stimulation (rTMS) has contributed to increase in the remission rate for patients with major depressive disorder (MDD). However, current rTMS treatment is practically inconvenient because it...
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Possible Modulatory Role of ARC Gene Variants in Mood Disorders

Crisafulli C, Calabrò M, Mandelli L, Wang SM, Lee SJ, Han C, Patkar A, Masand P, Pae CU, Souery D, Mendlewicz J, Serretti A

Objective: The genetic background of mood disorders is gradually emerging through the use of large multicenter samples but a detailed phenotyping is complementary in elucidating the role of modulating variants. Methods:...
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Biomarkers of Major Depressive Disorder: Knowing is Half the Battle

Malik S, Singh R, Arora G, Dangol A, Goyal S

Major depressive disorder (MDD) is a heterogeneous disease which is why there are currently no specific methods to accurately test the severity, endophenotype or therapy response. This lack of progress...
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Korean Medication Algorithm for Depressive Disorder 2021, Fourth Revision: An Executive Summary

Seo JS, Bahk WM, Woo YS, Park YM, Kim W, Jeong JH, Shim SH, Lee JG, Jang SH, Yang CM, Wang SM, Jung MH, Sung HM, Choo IH, Yoon BH, Lee SY, Jon DI, Min KJ

Objective: In the 19 years since the Korean College of Neuropsychopharmacology and the Korean Society for Affective Disorders developed the Korean Medication Algorithm Project for Depressive Disorder (KMAP-DD) in 2002,...
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Comparison of Mismatch Negativity According to Suicidal Ideation in Patients With Major Depressive Disorder

Lee M, Lee YJ, Hwang J, Woo Si, Kim MJ, Kang B, Kim Y, Hahn SW

Objective : Mismatch negativity (MMN) is known to reflect several abnormalities of cognitive function-ing. This study is aimed to investigate the differences in MMN among major depressive disorder (MDD) patients...
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Comparisons of Heart Rate Variability Parameters between Depressive Disorder and Trauma and Stressor Related Disorders

Kim MC, Park S, Lee JH

  • KMID: 2522090
  • J Korean Soc Biol Ther Psychiatry.
  • 2021 Oct;27(3):200-207.
Objectives:Depression and stress-related response is common symptoms in mental health outpatients. The purpose of this study was to investigate the differences of change in heart rate variability parameters between patients...
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The Impact of Depressive Symptom on Efficacy and Compliance of Positive Airway Pressure in Obstructive Sleep Apnea

Lee SY, Kim SH, Bang YR, Jang SH, Bae WY, Kim Sj

  • KMID: 2522089
  • J Korean Soc Biol Ther Psychiatry.
  • 2021 Oct;27(3):190-199.
Objectives:The aim of this study was to determine how the efficacy and compliance of positive airway pressure (PAP) varies depending on the depressive symptom with obstructive sleep apnea (OSA). Methods:We collected...
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Alterations in the Occipital Cortex of Drug-Naïve Adults With Major Depressive Disorder: A Surface-Based Analysis of Surface Area and Cortical Thickness

Lee JS, Kang W, Kang Y, Kim A, Han KM, Tae WS, Ham BJ

Objective Advances in surface-based morphometric methods have allowed researchers to separate cortical volume into cortical thickness (CTh) and surface area (SA). Although CTh alterations in major depressive disorder (MDD) have...
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Heart Rate Variability and Its Ability to Detect Worsening Suicidality in Adolescents: A Pilot Trial of Wearable Technology

Sheridan DC, Baker S, Dehart R, Lin A, Hansen M, Tereshchenko LG, Le N, Newgard CD, Nagel B

Objective Suicide is the 2nd leading cause of death in adolescence, and acute pediatric mental health emergency department (ED) visits have doubled in the past decade. The objective of this...
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