Korean J Perinatol.  2016 Jun;27(2):122-126. 10.14734/kjp.2016.27.2.122.

A Case of Rotavirus Infection Presenting with Direct Hyperbilirubinemia

• Ha JS
• Lee SH
• Yoo TY
• Park HW
• Kim MH

• KMID: 2316290
• DOI: http://doi.org/10.14734/kjp.2016.27.2.122

Abstract

Rotavirus is the most common cause of infectious gastroenteritis in infants and young children and estimated to cause more than 111 million cases of diarrhea annually. Most patients show no specific symptom or experience mild fever, vomiting, non-bloody diarrhea and symptoms often resolve within several days. However, some of patients suffer from severe complication such as necrotizing enterocolitis, intussusception, seizure, encephalitis, and cholestasis. We report a neonatal case of rotavirus infection presenting with reversible direct hyperbilirubinemia with a brief review of associated literatures.

Keyword

Rotavirus infection; Newborn; Direct hyperbilirubinemia

MeSH Terms

Child
Cholestasis
Diarrhea
Encephalitis
Enterocolitis, Necrotizing
Fever
Gastroenteritis
Humans
Hyperbilirubinemia*
Infant
Infant, Newborn
Intussusception
Rotavirus Infections*
Rotavirus*
Seizures
Vomiting

Figure

• 

  Fig. 1 The trend of total bilirubin and direct bilirubin during hospitalization and follow-up after discharge from hospital. Abbreviations: HD, hospital day; DD, day after discharge.

• 

  Fig. 2 The findings of hepatobiliary scan on the 8th hospital days. 99mTc-3-bromo-2,4,6-trimethyl-IDA hepatobiliary scintigraphy of patient shows no passage disturbance of radiotracer in biliary tree and no evidence of biliary atresia.

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