Korean J Urol.  2013 Dec;54(12):884-887.

Spermatocytic Seminoma With Sarcoma: An Indication for Adjuvant Chemotherapy in Localized Disease

• Wetherell
• Lawrentschuk N
• Gyomber D

Abstract

Spermatocytic seminoma (SCS) with sarcoma is an extremely rare testicular tumor with only 11 cases previously described in the literature. We present the 12th case of SCS with sarcoma in a 29-year-old male. SCS itself is an uncommon germ cell tumor with a relatively indolent clinical course that mostly affects males around the fifth decade of life. Sarcomatous differentiation of SCS occurs in 5% to 6% of cases and correlates with a higher possibility of metastatic disease and a poor prognosis. Clinically, this tumor manifests as a slow-growing testicular mass often with an accelerated period of secondary growth. After a concise review of the literature, we conclude that SCS with sarcoma should be treated by radical inguinal orchidectomy with strong consideration given to adjuvant chemotherapy.

Keyword

Orchiectomy; Sarcoma; Seminoma; Testicular neoplasms; Testis

MeSH Terms

Adult
Chemotherapy, Adjuvant*
Humans
Male
Neoplasms, Germ Cell and Embryonal
Orchiectomy
Prognosis
Sarcoma*
Seminoma*
Testicular Neoplasms
Testis

Figure

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  FIG. 1 Gray-scale ultrasound scan demonstrating a large cystic mass in the right testis.

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  FIG. 2 Microscopic chondroid-type change demonstrating sarcoma differentiation (×200).

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  FIG. 3 Microscopic demonstration of the interface between the sarcoma (top right) and seminoma (bottom left) elements (×40).

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