Pediatr Gastroenterol Hepatol Nutr.  2012 Sep;15(3):175-182.

A Clinical Study of the Relationship between Obesity and Pubertal Development in Girls

Affiliations
  • 1Department of Pediatrics, Hallym University Medical Center, Chuncheon, Korea. ohphilia@unitel.co.kr

Abstract

PURPOSE
Recently, public interest in obesity and earlier pubertal development has been increasing. The purpose of this study was to analyze the relationship between obesity and pubertal development in girls.
METHODS
A total of 158 girls presenting with earlier pubertal development from July 2008 to June 2010 were included in the study. Their mean age was 8.27+/-1.3 years and the mean bone age advancement was 1.86+/-0.3 years.
RESULTS
Based on weight-for-height percentiles, their obesity rate was 9.2% and overweight rate was 15.8%. However, for body mass index (BMI), the result was a bit different; with an obesity rate of 13.2% and overweight rate of 24.3%. About 40% of the girls had a family history of early maturation. Among them, 25.7% had a maternal history, 4.6% paternal and 7.2% both. However, 60% of them had no family history. We then classified these girls into families with one son and one daughter, and those with two daughters. In one-son/one-daughter families, 69.3% were the first children and 30.7% were second. In two-daughter families, 65.3% were the first and 34.7% were second. We found that 67.5% had a history of taking herbal medicine.
CONCLUSION
The obesity and overweight rates in girls with earlier pubertal development were higher than those of normal girls, but with a small discrepancy between weight-for-height percentile and BMI-based results. Furthermore, taking herbal medicine seems to be a potential factor for earlier pubertal development in Korea.

Keyword

Earlier pubertal development; Obesity; Weight-for-height percentile; Body mass index; Herbal medicine

MeSH Terms

Body Mass Index
Child
Herbal Medicine
Humans
Isothiocyanates
Korea
Nuclear Family
Obesity
Overweight
Isothiocyanates

Figure

  • Fig. 1 Height percentiles of girls with earlier pubertal development.

  • Fig. 2 Weight-for-height percentiles of girls with earlier pubertal development.

  • Fig. 3 Types of milk feeding in infancy.

  • Fig. 4 Family relationships of the girls with earlier pubertal development. *p-value=0.0019, †p-value=0.0321.


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