Pediatr Allergy Respir Dis.
2008 Sep;18(3):260-265.
A case of Swyer-James Syndrome Successfully Treated with Methylprednisolone Pulse Therapy
- Affiliations
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- 1Department of Pediatrics and Asthma Allergy Center, Inje University Sanggye Paik Hospital, Seoul, Korea. kimck@sanggyepaik.ac.kr
- 2Department of Radiology, Inje University Sanggye Paik Hospital, Seoul, Korea.
Abstract
- Swyer-James syndrome (SJS) is characterized by a small- or normal-sized unilateral hyperlucent lung with decreased vascularity and air trapping on plain radiographs. SJS is considered to be a postinfectious form of bronchiolitis obliterans and has occurred following childhood pulmonary infection by adenovirus, measles, influenza virus, Bordetella pertussis, Mycobacterium tuberculosis or Mycoplasma pneumoniae. The standard treatment modality for SJS is supportive care. Despite the prominent role of inflammation in the pathogenesis of SJS, the use of corticosteroids has remained controversial. We report herein a case of SJS which was successfully treated with monthly methylprednisolone pulse therapy, resulting in complete remission as verified by high resolution computed tomography.
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