Nat Prod Sci.
2015 Sep;21(3):147-149. 10.0000/nps.2015.21.3.147.
Antibiotic Components from the Rhizomes of Curcuma zedoaria
- Affiliations
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- 1College of Pharmacy, Duksung Women's University, Seoul 132-714, Korea. sangheeshim@duksung.ac.kr
- KMID: 2312888
- DOI: http://doi.org/10.0000/nps.2015.21.3.147
Abstract
- Two terpenoids, including one uniquely aromatized one (1), were isolated from CH2Cl2-soluble fraction of MeOH extracts of Curcuma zedoaria. They were identified to be a sesquiterpene ketolactone (1) and orobanone (2), respectively on the basis of their NMR data. The structure of compound 1 was confirmed by X-ray chrystallography and the reported NMR assignments for 1 were revised in this study. Antibiotic activities for compounds 1 and 2 were evaluated using disk diffusion assay. Compound 1 showed potent antibacterial activities against Listeria monocytogenes and Staphylococcus pseudointermedius while compound 2 was active against Bacillus cereus.
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