Lab Med Online.  2013 Apr;3(2):75-78.

PCR-based Investigation of Infection Patterns in Patients with Pelvic Inflammatory Diseases in Jeju

• Kim WJ
• Lee K
• Kim DL

Abstract

BACKGROUND
Pelvic inflammatory disease (PID) is a microbial infection caused by the upward spread of infectious organisms through the cervical os. Early diagnosis and treatment of PID are essential for the prevention of sequelae such as ectopic pregnancies, infertility, and chronic pelvic pain. Although Chlamydia trachomatis and Neisseria gonorrhoeae are well-known causal agents of PID, there have been reports on some changes in PID-associated infection. The aim of this study was to investigate the infection patterns in patients with PID in Jeju.
METHODS
Endocervical samples obtained from 65 patients with PID were tested for C. trachomatis, Mycoplasma genitalium, Mycoplasma hominis, N. gonorrhoeae, Trichomonas vaginalis, and Ureaplasma urealyticum using multiplex PCR.
RESULTS
The samples were positive for C. trachomatis (63%), M. hominis (34%), U. urealyticum (20%), M. genitalium (17%), N. gonorrhoeae (9%), and T. vaginalis (6%).
CONCLUSIONS
This study showed that C. trachomatis infection was prevalent and the incidence of M. hominis was higher than that of U. urealyticum.

Keyword

Pelvic inflammatory disease; Chlamydia trachomatis; PCR

MeSH Terms

Chlamydia trachomatis
Early Diagnosis
Female
Humans
Incidence
Infertility
Mycoplasma genitalium
Mycoplasma hominis
Neisseria gonorrhoeae
Pelvic Inflammatory Disease
Pelvic Pain
Polymerase Chain Reaction
Pregnancy
Pregnancy, Ectopic
Trichomonas vaginalis
Ureaplasma urealyticum

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