Lab Anim Res.  2010 Jun;26(2):215-218.

A Tumoral Calcinosis Case in a Beagle Dog

Affiliations
  • 1College of Veterinary Medicine, Chungbuk National University, Cheongju, Korea. bwahn@cbu.ac.kr

Abstract

We describe a case of tumoral calcinosis in a 13-month-old female Beagle dog presenting for surgical removal of a 4x3x3 cm mass in the soft tissues of the medial right shoulder joint. On radiologic examination, the mass showed increased radiopacity. Blood analysis data indicated chronic renal failure with hyperphosphatemia and hypercalcemia. Grossly, the mass was irregular, round and multilocular, with hard consistency. Histologically, there were many variable-sized loculi surrounded by capsule and interstitial connective tissues were generated among the loculi. Inflammatory cells, fibroblasts, fibrocytes and multinucleated giant cells were present at the margins of the loculi. Most of the loculi were filled with calcium or chalky material. To our knowledge, this is the first case of tumoral calcinosis in Korea.

Keyword

Beagle dog; case report; tumoral calcinosis

MeSH Terms

Animals
Calcinosis
Calcium
Connective Tissue
Dogs
Female
Fibroblasts
Giant Cells
Humans
Hypercalcemia
Hyperphosphatemia
Infant
Kidney Failure, Chronic
Korea
Shoulder Joint
Calcium
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