Lab Med Online.  2016 Jul;6(3):187-190. 10.3343/lmo.2016.6.3.187.

A Case of Septic Shock Following Catheter-related Infection Caused by Lactococcus lactis subsp. lactis in an Adult

Affiliations
  • 1Department of Laboratory Medicine, Chonbuk National University Medical School, Jeonju, Korea. choyg@jbnu.ac.kr
  • 2Research Institute of Clinical Medicine of Chonbuk National University-Biomedical Research Institute of Chonbuk National University Hospital, Jeonju, Korea.
  • 3Chonbuk National University Hospital Branch of National Culture Collection for Pathogens, Jeonju, Korea.

Abstract

Lactococcus lactis is a gram-positive cocci used extensively in the dairy industry, but considered an unusual pathogen in humans. Among its five subspecies, L. lactis subsp. lactis in particular has rarely been reported as a pathogen. We report a case of septic shock caused by L. lactis subsp. lactis in an adult patient. A 64-yr-old male patient was admitted to outpatient clinics, with chief complaints of fever and chills for one week after convalescent hospital admission. He had severe ileus requiring surgery. He had a peripherally inserted central catheter from convalescent hospital, which was immediately removed. From two sets of blood and catheter tip cultures, we identified L. lactis subsp. lactis using the Vitek 2 system (bioMerieux Inc., USA), and confirmed this result by 16S rRNA sequencing. The patient was empirically treated with ciprofloxacin, and he recovered and was discharged.

Keyword

Lactococcus lactis subsp. lactis; Catheter-related infections; Septic shock

MeSH Terms

Adult*
Ambulatory Care Facilities
Catheter-Related Infections*
Catheters
Chills
Ciprofloxacin
Fever
Gram-Positive Cocci
Hospitals, Convalescent
Humans
Ileus
Lactococcus lactis*
Lactococcus*
Male
Shock, Septic*
Ciprofloxacin

Reference

1. Lodics TA, Steenson LR. Phage-host interactions in commercial mixed-strain dairy starter cultures: practical significance―a review. Journal of Dairy Science. 1993; 76:2380–91.
Article
2. Guz G, Colak B, Hizel K, Suyani E, Sindel S. Peritonitis due to Lactococcus lactis in a CAPD patient. Scand J Infect Dis. 2006; 38:698–9.
Article
3. Lee JY, Seo MY, Yang J, Kim K, Chang H, Kim SC, et al. Polymicrobial peritonitis with Lactococcus lactis in a peritoneal dialysis patient. Chonnam Med J. 2014; 50:67–9.
4. Guz G, Yegin ZA, Dogan I, Hizel K, Bali M, Sindel S. Portal vein thrombosis and liver abscess due to Lactococcus lactis. Turk J Gastro-enterol. 2006; 17:144–7.
5. Inoue M, Saito A, Kon H, Uchida H, Koyama S, Haryu S, et al. Subdural empyema due to Lactococcus lactis cremoris: case report. Neurol Med Chir (Tokyo). 2014; 54:341–7.
Article
6. Uchida Y, Morita H, Adachi S, Asano T, Taga T, Kondo N. Bacterial meningitis and septicemia of neonate due to Lactococcus lactis. Pediatr Int. 2011; 53:119–20.
Article
7. Glikman D, Sprecher H, Chernokozinsky A, Weintraub Z. Lactococcus lactis catheter-related bacteremia in an infant. Infection. 2010; 38:145–6.
Article
8. Karaaslan A, Soysal A, Sarmis A, Kadayifci EK, Cerit K, Atici S, et al. Lactococcus lactis catheter-related bloodstream infection in an infant: case report. Jpn J Infect Dis. 2015; 68:341–2.
9. Hadjisymeou S, Loizou P, Kothari P. Lactococcus lactis cremoris infection: not rare anymore? BMJ Case Rep. 2013.
Article
10. Mofredj A, Bahloul H, Chanut C. Lactococcus lactis: an opportunistic bacterium? Med Mal Infect. 2007; 37:200–7.
11. Lin KH, Sy CL, Chen CS, Lee CH, Lin YT, Li JY. Infective endocarditis complicated by intracerebral hemorrhage due to Lactococcus lactis subsp. cremoris. Infection. 2010; 38:147–9.
12. Langer AJ, Ayers T, Grass J, Lynch M, Angulo FJ, Mahon BE. Nonpas-teurized dairy products, disease outbreaks, and state laws-United States, 1993-2006. Emerg Infect Dis. 2012; 18:385–91.
Article
13. Drouault S, Corthier G, Ehrlich SD, Renault P. Survival, physiology, and lysis of Lactococcus lactis in the digestive tract. Appl Environ Microbiol. 1999; 65:4881–6.
14. Plumed-Ferrer C, Barberio A, Franklin-Guild R, Werner B, McDonough P, Bennett J, et al. Antimicrobial susceptibilities and random amplified polymorphic DNA-PCR fingerprint characterization of Lactococcus lactis ssp. lactis and Lactococcus garvieae isolated from bovine intra-mammary infections. J Dairy Sci. 2015.
Article
15. Zechini B, Cipriani P, Papadopoulou S, Di Nucci G, Petrucca A, Teggi A. Endocarditis caused by Lactococcus lactis subsp. lactis in a patient with atrial myxoma: a case report. Diagn Microbiol Infect Dis. 2006; 56:325–8.
Article
Full Text Links
  • LMO
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr