Korean J Nephrol.
1999 Sep;18(5):820-824.
A Case of Crescentic Glomerulonephritis Associated with Bacterial Endocarditis
- Affiliations
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- 1Department of Nephrology, School of Medicine, Ajou University, Suwon, Korea.
- 2Department of Cardiology, School of Medicine, Ajou University, Suwon, Korea.
- 3Department of Pathology, School of Medicine, Ajou University, Suwon, Korea.
Abstract
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A 25-year-old male presented with mitral insufficiency, perimembranous type of ventricular
septal defect, pulmonary edema and renal insufficiency. The initial serum creatinine level
was 16.2mg/dl. Blood cultures were positive for Streptococcus viridans and appropriate
antibiotic therapy was initiated. Renal biopsy revealed diffuse proliferative
glomerulonephritis with crescents involving all of the glomeruli. Even after adequate
duration of treatment with antibiotics, surgical therapy, and high dose steroid therapy,
renal function did not recover and the patient ended up with continuous ambulatory
peritoneal dialysis. We present a case of crescentic glomerulonephritis associated
with bacterial endocarditis with a review of the literature.