Korean J Med.  2009 Mar;76(3):358-364.

Recovery from crescentic glomerulonephritis with bacterial endocarditis with antibiotics alone

Affiliations
  • 1Department of Internal Medicine, Kidney Research Institute, College of Medicine, Hallym University, Seoul, Korea. jwn8671@unitel.co.kr
  • 2Department of Pathology, College of Medicine, Hallym University, Seoul, Korea.
  • 3Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.

Abstract

A 59-year-old woman presented to our hospital with fever, petechiae, pyuria, gross hematuria, and rapidly progressive glomerulonephritis (GN). She had a history of urinary tract infection. A renal biopsy specimen revealed crescentic GN and an echocardiogram showed a vegetation 3.15x1.73 cm in size on the mitral valve and severe mitral valve regurgitation. Blood cultures grew Enterococcus faecalis. Treatment with antibiotics alone resulted in clinical improvement of the renal function and resolution of the fever. Three months after hospitalization, the echocardiogram showed mild mitral valve regurgitation. This case suggests that crescentic glomerulonephritis associated with even a huge vegetation of infectious endocarditis can be treated with antibiotics alone and result in stable renal function.

Keyword

Endocarditis; Glomerulonephritis; Antibiotics

MeSH Terms

Anti-Bacterial Agents
Biopsy
Endocarditis
Endocarditis, Bacterial
Enterococcus faecalis
Female
Fever
Glomerulonephritis
Hematuria
Hospitalization
Humans
Middle Aged
Mitral Valve
Mitral Valve Insufficiency
Purpura
Pyuria
Urinary Tract Infections
Anti-Bacterial Agents
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