Korean J Nephrol.
2005 Sep;24(5):828-831.
A Case of Lupus Nephritis Associated with Transiently Decreased C1 Inactivator Activity and Angioedema
- Affiliations
-
- 1Department of Internal Medicine, Chonbuk National University Medical School, Korea. kwon@chonbuk.ac.kr
- 2Department of Pathology, Chonbuk National University Medical School, Korea.
- 3Institute for Clinical Sciences, Jeonju, Korea.
Abstract
- C1 esterase inhibitor deficiency with consequent angioedma is an uncommon condition. Nonhereditary C1 inhibitor deficiency includes underlying disorders; lymphoproliferative disorder, autoimmune disease, hypereosinophilia, drug-induced, allergic, and idiopathic forms. The as sociation of hereditary C1 esterase inhibitor deficiency with systemic lupus erythematosus has been previously described. We experienced a case with transiently decreased C1 inactivator activity and angioedema in lupus nephritis. This present case is a previously healthy 22-year-old woman, who developed intermittent facial angioedema and decreased urine amount. After steroid treatment, the C1 inactivator activity was recovered and angioedema was disappeared.
