Korean J Helicobacter Up Gastrointest Res.  2016 Jun;16(2):68-72. 10.7704/kjhugr.2016.16.2.68.

Factors Influencing Gastric Microbiota

Affiliations
  • 1Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea. ppakongs@daum.net

Abstract

Researches on microbiota in the stomach have entered a revolutionary period in recent years due to the advanced technology that can detect culture-independent gastric microfloras. In spite of its harsh environment, stomach plays a role as an ecosystem for some microbiota. Their composition and number of colony forming units are influenced by several innate defense mechanisms such as low gastric pH, gastric mucus layer, migrating motor complex and some external factors such as gastric acid lowering medications and diet patterns. Here, we review the literatures concerning factors that influence the gastric microbiota.We believe this will be helpful for understanding the role of microbiota in the stomach.

Keyword

Stomach; Microbiota; Gastic acid; Proton pump inhibitors; Gastric juice

MeSH Terms

Defense Mechanisms
Diet
Ecosystem
Gastric Acid
Gastric Juice
Hydrogen-Ion Concentration
Microbiota*
Mucus
Myoelectric Complex, Migrating
Proton Pump Inhibitors
Stem Cells
Stomach
Proton Pump Inhibitors
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