Korean J Helicobacter Up Gastrointest Res.  2013 Mar;13(1):69-72. 10.7704/kjhugr.2013.13.1.69.

Upper Gastrointestinal Hemorrhage from Esophageal Ulcer Caused by Coinfection of Herpes Simplex Virus and Cytomegalovirus in Immunocompromised Patient

• Chung HH
• Jang JY
• Byun JM
• Park SH
• Kim DH
• Chang YW

• KMID: 2305170
• DOI: http://doi.org/10.7704/kjhugr.2013.13.1.69

Abstract

Coinfection with herpes simplex virus and cytomegalovirus is a very rare cause of esophageal ulcer and upper gastrointestinal hemorrhage. A 26 year-old male kidney transplant recipient was referred with a complaint of melena. Upper gastrointestinal endoscopy showed a huge esophageal ulcer in the anastomosis site of the esophagogastrostomy. The ulcer occupied about two-thirds of the circumference of the esophageal lumen and an exposed vessel in the ulcer base was noted. Pathologic findings with immunohistochemical stain showed co-infection of herpes simplex virus and cytomegalovirus. He was treated successfully with endoscopic hemostasis and antiviral therapy. We report a case of upper gastrointestinal hemorrhage from esophageal ulcer caused by coinfection of herpes simplex virus and cytomegalovirus.

Keyword

Esophageal ulcer; Simplexvirus; Cytomegalovirus; Gastrointestinal hemorrhage; Immunocompromised host

MeSH Terms

Coinfection
Cytomegalovirus
Endoscopy, Gastrointestinal
Gastrointestinal Hemorrhage
Glycosaminoglycans
Hemostasis, Endoscopic
Herpes Simplex
Humans
Immunocompromised Host
Kidney
Male
Melena
Methylmethacrylates
Polystyrenes
Simplexvirus
Ulcer
Glycosaminoglycans
Methylmethacrylates
Polystyrenes