Korean J Dermatol.  2003 Feb;41(2):227-231.

A Case of T-cell Lymphoblastic Lymphoma Involving the Skin

Affiliations
  • 1Department of Dermatology, Catholic University of Daegu School of Medicine, Daegu, Korea.
  • 2Department of Pathology, Catholic University of Daegu School of Medicine, Daegu, Korea.

Abstract

Lymphoblastic lymphoma(LBL) is non-Hodgkin's lymphoma with a high tendency of rapid progression to acute leukemia, but cutaneous infiltration is rare. Cutaneous lesions in LBL were largely red papules and nodules. We herein report a case of 24-year-old woman with T-cell LBL(TLBL) involving the skin. The lesions revealed 1~3 cm-sized, multiple confluent scaly patches on her face and back, and subsided about 4 weeks later during the period of follow-up and combination chemotherapy. Histologically there were perivascular, periadnexal and perineural infiltrates of medium-sized lymphoid cells in mid to deep dermis. The neoplastic cells had scant cytoplasm, very fine chromatin, and inconspicuous nucleoli and expressed CD5, CD45, CD45RO and TdT.

Keyword

T-cell lymphoblastic lymphoma; Scaly patches

MeSH Terms

Chromatin
Cytoplasm
Dermis
Drug Therapy, Combination
Female
Follow-Up Studies
Humans
Leukemia
Lymphocytes
Lymphoma, Non-Hodgkin
Precursor Cell Lymphoblastic Leukemia-Lymphoma*
Skin*
T-Lymphocytes*
Young Adult
Chromatin
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