Korean J Dermatol.  2003 Jun;41(6):808-810.

A Case of Cutaneous Metastasis of Signet-Ring Cell Gastric Carcinoma

Affiliations
  • 1Department of Dermatology, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea. cdk270@plaza2.snu.ac.kr

Abstract

Signet-ring cell(SRC) is formed by intracytoplasmic accumulation of various substances which push the nucleus to the cellular border so that the cell looks like a signet ring. Most cutaneous SRC neoplasms are metastatic adenocarcinomas. SRC, when seen in skin, may indicate that the primary origins are from the stomach, colon or breast. The SRC formations in cutaneous neoplasms other than metastatic adenocarcinoma have also been reported such as SCC, BCC, metastatic melanoma etc. We experienced a case of cutaneous metastasis of SRC gastric carcinoma which the first symptom was skin lesion of the scalp.

Keyword

Signet-ring cell; Cutaneous metastasis

MeSH Terms

Adenocarcinoma
Breast
Colon
Melanoma
Neoplasm Metastasis*
Scalp
Skin
Stomach
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