Korean J Dermatol.  2019 Dec;57(10):629-631.

A Skin Metastasis from a Gastric Signet-Ring Cell Carcinoma in an Adolescent that Mimicked Steatocystoma Multiplex

• Choi ME
• Lee WJ
• Chang SE
• Lee MW
• Choi JH
• Paik SH

Abstract

Cutaneous metastases of internal malignancies are relatively rare and originate most frequently from tumors of the breast and lung. Herein, we present an unusual clinical presentation of a skin metastasis from a gastric signet-ring cell carcinoma in an adolescent. A 19-year-old boy presented with asymptomatic subcutaneous nodules on his abdomen and back. Histopathological examination revealed signet-ring cells with cytoplasmic mucin in the dermis. A diagnosis of cutaneous metastasis of a signet-ring cell carcinoma was made and the patient died 12 days after his initial visit to our dermatology clinic. Gastric carcinomas have infrequently been reported in adolescents, and cutaneous metastases from carcinomas in this group are extremely rare. Clinicians should be aware that skin metastases of adolescent gastric carcinoma can be similar in presentation to steatocystoma multiplex and that a skin biopsy is necessary for suspicious skin lesions.

Keyword

Signet ring cell carcinoma; Skin; Neoplasm metastasis; Adolescent; Steatocystoma multiplex

MeSH Terms

Abdomen
Adolescent*
Biopsy
Breast
Carcinoma, Signet Ring Cell
Cytoplasm
Dermatology
Dermis
Diagnosis
Humans
Lung
Male
Mucins
Neoplasm Metastasis*
Skin*
Steatocystoma Multiplex*
Young Adult
Mucins