Korean J Dermatol.  2004 May;42(5):637-639.

A Case of Pyoderma Gangrenosum Treated with Topical Tacrolimus and Oral Cyclosporin

• Kim HS
• Yoon HJ
• Kim JA
• Cho KH

Abstract

Pyoderma gangrenosum is a chronic inflammatory skin disease, characterized by the recurring destructive and painful skin ulcers. Although the mainstay of therapy is the systemic administration of high doses of corticosteroids, many other treatment modalities have been widely used. Recently, there have been several reports of the successful treatment of pyoderma gangrenosum using topical tacrolimus. We report a successful treatment of pyoderma gangrenosum with combination therapy of topical tacrolimus and systemic cyclosporin.

Keyword

Cyclosporin; Pyoderma gangrenosum; Tacrolimus

MeSH Terms

Adrenal Cortex Hormones
Cyclosporine*
Pyoderma Gangrenosum*
Pyoderma*
Skin Diseases
Skin Ulcer
Tacrolimus*
Adrenal Cortex Hormones
Cyclosporine
Tacrolimus