Korean J Dermatol.
2004 Nov;42(11):1470-1474.
A Case of Cutaneous Polyarteritis Nodosa Associated With Chronic Hepatitis B Infection
- Affiliations
-
- 1Department of Dermatology, Seoul National University College of Medicine, Seoul, Korea.
- 2Seoul National University Bundang Hospital, Gyeonggi, Korea. vignette@snubh.org
Abstract
- Polyarteritis nodosa (PAN) is regarded as an immune-complex mediated vasculitis and can present as extrahepatic manifestation of hepatitis B virus (HBV) infection. When treating HBV-associated PAN with immunosuppressive agent such as systemic steroid, the possibility of viral reactivation should be kept in mind and eagerly checked. Herein we report a case of HBV-associated cutaneous polyarteritis nodosa and its treatment outcome with combination therapy of steroid and antiviral agent, lamivudine for 6 weeks. Our experience suggests that more clinical data should be collected to determine the proper indication and end-point of antiviral therapy in chronic HBV carriers who receive immunosuppressant therapy.
