Korean J Dermatol.  2007 Aug;45(8):832-835.

A Case of Simultaneous Occurrence of Vitiligo-like and Morphea-like Lesion in Recipient of Allogenic Bone Marrow Transplantation

• Kim HD
• Won TH
• Seo PS
• Yoon NH
• Park SD

Abstract

Vitiligo and morphea are two distinct entities of unknown etiology, although their existence implies that the immune system and/or the central or peripheral nervous system has been incriminated. Only a few reports of their simultaneous occurrence are on record. Here we report a case of a 39 year old woman affected with both vitiligo of the face, chest and hand and morphea of shoulder and trunk. Since the two diseases appeared after bone marrow transplantation, if could be deduced that there is a possible association between them. Two diseases observed simultaneously in this patient may be derived from the common pathomechanism. An autoimmune etiology is thought to play a part in both of these diseases.

Keyword

Bone marrow transplantation; Chronic GVHD; Morphea; Vitiligo

MeSH Terms

Adult
Bone Marrow Transplantation*
Bone Marrow*
Female
Hand
Humans
Immune System
Peripheral Nervous System
Scleroderma, Localized
Shoulder
Thorax
Vitiligo