Korean J Dermatol.
2008 Feb;46(2):259-263.
A Case of Localized Urticaria Induced by Mesotherapy
- Affiliations
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- 1Department of Dermatology, College of Medicine, Our Lady of Mercy Hospital, The Catholic University of Korea, Incheon, Korea. leejd@olmh.cuk.ac.kr
Abstract
- Mesotherapy is a widely used technique of intradermal or subcutaneous microinjection of a drug or cocktail of drugs, at sites of the body with medical or aesthetic problems. Rare cutaneous side effects have been previously reported, including allergic reactions to the administered drugs or skin infections. We herein report a case of an immediate adverse reaction following mesotherapy. A 40-year-old woman was referred to our department with pruritic erythematous urticarial plaques at the sites of application of mesotherapy. She had been treated for abdominal liposis with one session of multiple subcutaneous injections of a drug mixture including aminophylline at a local clinic. After clinical recovery, a skin test using the same drugs was performed. A positive intradermal test was found with aminophylline and ethylenediamine that is an ingredient of aminophylline. These results support that the ethylenediamine component of aminophylline is identified as the etiologic agent.
