Korean J Dermatol.  2010 Mar;48(3):240-242.

A Case of Primary Syphilis on Both Oral Angles

• Bae EJ
• Seo SH
• Kye YC
• Ahn HH

Abstract

Primary syphilis affects the genital and, less frequently, the extragenital regions. Approximately two-thirds of extragenital chancres occur above the neck, and about one-half of these are seen on the lips, the perioral region, or in the oral cavity. We present a case of a 32-year-old woman with a 2-month history of discharging ulcers on both oral angles. She had a history of orogenital sexual contact. Serologic tests for syphilis was positive, particularly the VDRL (1:128), confirmed by TPHA. The biopsy specimen showed a predominant infiltration of plasma cells in the dermis. The skin lesions improved after 4 weeks treatment with doxycycline.

Keyword

Extragenital chancre; Oral angle; Orogenital sexual contact

MeSH Terms

Adult
Biopsy
Chancre
Dermis
Doxycycline
Female
Humans
Lip
Mouth
Neck
Plasma Cells
Serologic Tests
Skin
Syphilis
Ulcer
Doxycycline
Syphilis