Korean J Blood Transfus.
2008 Dec;19(3):245-249.
A Case of RhD with Anti-D
- Affiliations
-
- 1Department of Laboratory Medicine, College of Medicine, Korea University, Seoul, Korea. malarim@korea.ac.kr
- 2Department of Laboratory Medicine, Seoul National University College of Medicine, Seoul, Korea.
Abstract
- We report here on a case of a RhD blood group phenotype with anti-D. The RhD phenotype for partial D phenotyping with using six monoclonal anti-sera typed as normal RhD for this case. DNA sequencing analysis of the RhD gene covering intron 8 to exon 10 showed two AAATAAGATA insertion sites in intron 8 and a single nucleotide change in the exon 10 area as compared with the normal RhD gene. However, the functional role of the RhD antigen is unclear.